Article

Glial and Neuronal Alzheimer's Disease-Related Alterations Reproduced in Human Induced Pluripotent Stem Cells With Presenilin-1 Mutation

2026-01-19

Abstract excerpt

<title>Abstract</title> Background A pathogenetic role of glial cells has been established virtually in all neurodegenerative disorders. In Alzheimer's disease (AD), together with β-amyloid deposition and the formation of fibrillary tangles, neuroinflammation contributes to neuronal dysfunction associated with the disease. Thus, selective control of glial cell activation becomes part of the multifactorial t...

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Literature Corpus work: f0fd148d-649a-512b-a6db-d79ceb24f2c6
DOI: 10.21203/rs.3.rs-8549806/v1

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