Article

Neurons from individual early Alzheimer’s disease patients reflect their clinical vulnerability

2021-11-11

Abstract excerpt

Establishing preclinical models of Alzheimer’s disease that predict clinical outcomes remains a critically important, yet to date not fully realised, goal. Models derived from human cells offer considerable advantages over non-human models, including the potential to reflect some of the inter-individual differences that are apparent in patients. Here we report an approach using induced pluripotent stem cell-derive...

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Literature Corpus work: b71b3673-11cc-53c4-b142-6764c358c7e6
DOI: 10.1101/2021.11.09.467891

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