Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals.

doi:10.1038/344463a0

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Article

Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals.

Nature - 29 Mar 1990

Jamal S, Ziff E

Abstract excerpt

A primary response to many growth factor-induced transmembrane signals is the rapid activation of transcription of the proto-oncogene c-fos and other early-response genes, including the beta-actin gene. The c-raf gene encodes a cytoplasmic serine/threonine kinase, raf-1, whose activity is also re...

Topics

Actins
Animals
Base Sequence
Cell Line
Cell Membrane
Chloramphenicol O-Acetyltransferase
Cloning, Molecular
Fibroblasts
Humans
Mice
Molecular Sequence Data
Mutation
Oncogene Proteins v-raf
Plasmids
Promoter Regions, Genetic
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-fos

Source

Open in PubMed

Identifiers

PMID: 2157161
DOI: 10.1038/344463a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2157161-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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