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Article

An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes.

The Journal of biological chemistry - 25 Jul 1993

Miltenberger R J, Cortner J, Farnham P J

Abstract excerpt

The proto-oncogene Raf-1 is a cytoplasmic serine/threonine kinase implicated in the signaling process in cell proliferation. To determine if Raf-1 is sufficient and necessary to transmit mitogenic signals to growth-responsive genes, we examined the effect of constitutively activated (v-raf) or in...

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PMID: 8340392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8340392-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes.PMID 8340392Read ↗

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A dominant negative Raf-1 mutant prevents v-Src-induced transformation.Semantic proximity Read ↗

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