Article
Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element.
Nucleic acids research - 1 Feb 2001
Fritz G, Kaina B
Abstract excerpt
The gene encoding the Ras-related GTPase RhoB-specific is immediate-early inducible by genotoxic treatments. Regulation of transcriptional activation of rhoB is still unclear. Here we show that cells lacking either p53 or c-Fos are not different from wild-type cells with respect to the level of rhoB induction upon UV irradiation, indicating that these transcription factors are not crucial for stimulation of rhoB...
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