Article

Stability of Polygenic Scores Across Discovery Genome-Wide Association Studies

2021-06-18

Abstract excerpt

Polygenic scores (PGS) are commonly evaluated in terms of their predictive accuracy at the population level by the proportion of phenotypic variance they explain. To be useful for precision medicine applications, they also need to be evaluated at the individual patient level when phenotypes are not necessarily already known. Hence, we investigated the stability of PGS in European-American (EUR)- and African-Americ...

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Literature Corpus work: ee5a11ab-2669-54d7-b23b-82627c1c37d7
DOI: 10.1101/2021.06.18.449060

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