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Article

Phenome-wide analysis of genome-wide polygenic scores.

Molecular psychiatry - 1 Sept 2016

Krapohl E, Euesden J, Zabaneh D, Pingault J-B, Rimfeld K, von Stumm S, Dale P S, Breen G, O'Reilly P F, Plomin R

Abstract excerpt

Genome-wide polygenic scores (GPS), which aggregate the effects of thousands of DNA variants from genome-wide association studies (GWAS), have the potential to make genetic predictions for individuals. We conducted a systematic investigation of associations between GPS and many behavioral traits, the behavioral phenome. For 3152 unrelated 16-year-old individuals representative of the United Kingdom, we created 13...

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Identifiers

PMID: 26303664
DOI: 10.1038/mp.2015.126
PMCID: PMC4767701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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