Article

Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stress

2024-05-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Peripherally restricted cannabinoid CB1 receptor antagonists without central side effects hold promise for treating metabolic disorders including diabetes and obesity. In atherosclerosis, the specific effects of peripheral CB1 signaling in vascular endothelial cells (ECs) remain incompletely understood. <h4>Methods and results</h4> Endothelial expression of the CB1 encoding...

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Literature Corpus work: ee21f2eb-0299-5430-92a0-f12a379f4a96
DOI: 10.1101/2024.05.15.594375

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