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Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stress

2025-09-04

Abstract excerpt

<title>Abstract</title> <p>Peripherally restricted cannabinoid CB1 receptor antagonists without central side effects hold promise for treating metabolic disorders including diabetes and obesity. In atherosclerosis, the specific effects of peripheral endothelial CB1 signaling remain incompletely understood. Here, we report the expression of the CB1 encoding gene CNR1 in arterial endothelial cells of human plaques....

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Literature Corpus work
a5738917-a003-54c4-9857-4756cacfce9c
DOI
10.21203/rs.3.rs-6944788/v1
Open publication

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Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stressDOI 10.21203/rs.3.rs-6944788/v1
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