Article

Endothelial AGO1 Drives Vascular Inflammation and Atherosclerosis via a Non-Canonical Nuclear Mechanism

2025-05-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Endothelial cell (EC) dysfunction is a cause and consequence of vascular inflammation and lipid dysregulation in atherosclerosis, yet the molecular drivers linking EC dysfunction to systemic metabolic derangements remain incompletely understood. Moreover, whether inhibiting an endogenous gene in ECs can impact liver function, lipid profile, and the vascular inflammation in t...

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Literature Corpus work: b1ec0e66-545d-5a62-af2b-cc555d14338c
DOI: 10.1101/2025.05.01.651783

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