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Next Generation Sequencing Reveals a High Prevalence of HIV-1 Minority Variants and an Expanded Drug Resistance Profile Among Individuals Initiated to Antiretroviral Therapy in a Resource-constrained Setting

2023-03-29

Abstract excerpt

<h4>Introduction: </h4> Because next-generation sequencing (NGS) can detect minority mutations that have been linked to treatment failure but are missed by population Sanger sequencing, it has the potential to enhance HIV treatment monitoring. Comparing NGS based on the Illumina platform to Sanger sequencing, we assessed the clinical importance of NGS in HIV-1 medication resistance testing. Methods In this retro...

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Literature Corpus work: edea7362-d01a-5f2e-b3aa-64c5d457b8ab
DOI: 10.21203/rs.3.rs-2741155/v1

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