Article
Clinical implications of HIV-1 minority variants.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jun 2013
Li Jonathan Z, Kuritzkes Daniel R
Abstract excerpt
Technologic advances in human immunodeficiency virus type 1 (HIV-1) sequencing have revolutionized the study of antiretroviral drug resistance and are increasingly moving from the laboratory to clinical practice. These techniques are able to detect HIV-1 drug resistance mutations present at low frequencies not detectable by current HIV-1 genotyping assays. For a number of commonly used antiretroviral medications,...
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