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Article

Limited marginal utility of deep sequencing for HIV drug resistance testing in the age of integrase inhibitors

2018-09-12

Abstract excerpt

HIV drug resistance genotyping is a critical tool in the clinical management of HIV infections. Although resistance genotyping has traditionally been conducted using Sanger sequencing, next-generation sequencing (NGS) is emerging as a powerful tool due to its ability to detect lower frequency alleles. However, the value added from NGS approaches to antiviral resistance testing remains to be demonstrated. We compar...

Identifiers and source

Literature Corpus work
7037aa42-7e22-5af3-a82c-e87e2eaee6a5
DOI
10.1101/414995
Open publication

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Limited marginal utility of deep sequencing for HIV drug resistance testing in the age of integrase inhibitorsDOI 10.1101/414995
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