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Article

Primary HIV-1 Drug Resistant Minority Variants.

AIDS reviews - 1 Jan 2000

Chimukangara Benjamin, Samuel Reshmi, Naidoo Kogieleum, de Oliveira Tulio

Abstract excerpt

Primary HIV drug resistant mutations are mutations that occur in an HIV-infected individual prior to the initiation of antiretroviral therapy (ART). These mutations may arise by de novo mutagenesis or result from transmission. Drug resistant mutations (DRMs) may reduce the effectiveness of ART leading to inadequate virological outcomes. Currently, Sanger sequencing is the standard method for detection of DRMs to...

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PMID: 28182621

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