Article

A quantitative and predictive model for RNA binding by human Pumilio proteins

2018-08-29

Abstract excerpt

<h4>Summary</h4> High-throughput methodologies have enabled routine generation of RNA target sets and sequence motifs for RNA-binding proteins (RBPs). Nevertheless, quantitative approaches are needed to capture the landscape of RNA/RBP interactions responsible for cellular regulation. We have used the RNA-MaP platform to directly measure equilibrium binding for thousands of designed RNAs and to construct a predic...

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Literature Corpus work: edd8bec8-d905-592b-bd2b-1d220afa2c4b
DOI: 10.1101/403006

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