Article

Discovery of a Well-Folded Protein Interaction Hub Within the Human Long Non-Coding RNA <i>NORAD</i>

2023-08-07

Abstract excerpt

<h4>ABSTRACT</h4> The long non-coding RNA NORAD functions in maintaining genomic stability in humans via sequestering Pumilio proteins from the cytoplasm, and thereby modulating the gene expression of mRNA targets of Pumilio proteins. Despite its role in fundamental cellular pathways including chromosome segregation and DNA damage response, there have been limited structural and biophysical descriptions of NORA...

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Literature Corpus work: 6e041ae4-635c-5d0f-af37-7efee4a44f33
DOI: 10.1101/2023.08.07.552337

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