Article

Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn’s disease via the mesentery

2023-05-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Mesenchymal stem cells (MSCs) are novel therapeutics for treatment of Crohn’s disease. However, their mechanism of action is unclear, especially in disease-relevant chronic models of inflammation. Thus, we used SAMP-1/YitFc, a chronic and spontaneous murine model of small intestinal inflammation, to study the therapeutic effect and mechanism of human bone marrow-derived MSCs...

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Literature Corpus work: ed8d7b4c-1066-57ee-b6c6-4271da73c90e
DOI: 10.1101/2023.05.22.541829

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