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Article

Advances in mesenchymal stromal cell therapy in the management of Crohn's disease.

Expert review of gastroenterology & hepatology - 1 Feb 2018

Ibraheim Hajir, Giacomini Chiara, Kassam Zain, Dazzi Francesco, Powell Nick

Abstract excerpt

INTRODUCTION: The aim of therapy in Crohn's disease (CD) is induction and maintenance of remission, promotion of mucosal healing and restoration of quality of life. Even the best treatment regimes, including combinations of biologics and immunomodulators lack durable efficacy and have well documented side effects. Accordingly, there is an unmet need for novel therapies. Mesenchymal stromal cells (MSCs) are a...

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Identifiers

PMID: 29096549
DOI: 10.1080/17474124.2018.1393332

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MSC

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