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Insights into Modeling Inflammatory Bowel Disease from Stem Cell Derived Intestinal Organoids

29 Apr 2025

Abstract excerpt

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), is a multifactorial, immune-mediated condition marked by chronic gastrointestinal inflammation. This condition significantly impairs patients' quality of life and represents a major public health challenge globally. Pathogenesis of IBD arises from complex interplay among genetic predisposition, environmental factors,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40299197
DOI: 10.1007/s12015-025-10887-8

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