Article

Elucidating early intestinal stem cell response to bacterial infection

2024-09-19

Abstract excerpt

Intestinal stem cells (ISCs) are the regenerative force of the gut epithelium. Lgr5+-ISC have been shown to respond to changes in their microenvironment by coping with different metabolites, adapting to caloric changes, and recovering from injury and inflammation. However, how pathogenic bacteria affect adult stem cell regeneration and, as a consequence, the overall tissue adaption to infection has yet to be explo...

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Literature Corpus work: 2db4bb3c-26a7-5167-a632-51680e1c3b5a
DOI: 10.1101/2024.09.15.613128

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