Article

Retrospective analysis of<i>The Two Sister Study</i>using haplotype-based association testing to identify loci associated with early-onset breast cancer

2020-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Breast cancer is a polygenic disorder and is the leading cause of cancer related mortality among women. Early-onset breast cancer (EOBC) is diagnosed in women prior to 45 years-of-age and is associated with worse clinical outcomes, a more aggressive disease phenotype, and poor prognosis for disease-free survival. While substantial progress has been made in defining the genetics of breast cancer,...

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Literature Corpus work: ed65dee1-d6d1-5a42-99e9-059d7af95def
DOI: 10.1101/2020.12.04.20244251

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