Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

From candidate gene studies to GWAS and post-GWAS analyses in breast cancer.

Current opinion in genetics & development - 1 Feb 2015

Fachal Laura, Dunning Alison M

Abstract excerpt

There are now more than 90 established breast cancer risk loci, with 57 new ones, revealed through genome-wide-association studies (GWAS) during the last two years. Established high, moderate and low penetrance genetic variants currently explain ∼49% of familial breast cancer risk. GWAS-discovered variants account for 14%, and it is estimated that another 1000 yet-to-be-discovered loci could contribute an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammography

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25727315
DOI: 10.1016/j.gde.2015.01.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

From candidate gene studies to GWAS and post-GWAS analyses in breast cancer.PMID 25727315Read ↗

Dissecting the heritable risk of breast cancer: From statistical methods to susceptibility genes.Semantic proximity Read ↗

Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.Semantic proximity Read ↗

The genetics of breast cancer risk in the post-genome era: thoughts on study design to move past BRCA and towards clinical relevance.Semantic proximity Read ↗

Association analysis identifies 65 new breast cancer risk loci.Semantic proximity Read ↗

Breast cancer genetics: what we know and what we need.Semantic proximity Read ↗

Breast cancer susceptibility genes pile up.Semantic proximity Read ↗

Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.Semantic proximity Read ↗

Genome-wide association study identifies novel breast cancer susceptibility loci.Semantic proximity Read ↗

Genetic susceptibility to breast cancer.Semantic proximity Read ↗

Germline DNA variations in breast cancer predisposition and prognosis: a systematic review of the literature.Semantic proximity Read ↗

The impact of next generation sequencing on the analysis of breast cancer susceptibility: a role for extremely rare genetic variation?Semantic proximity Read ↗

Polygenic susceptibility to breast cancer: current state-of-the-art.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.