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Article

Identification of Novel Breast Cancer Risk Loci.

Cancer research - 1 Oct 2017

Chan Claire Hian Tzer, Munusamy Prabhakaran, Loke Sau Yeen, Koh Geok Ling, Wong Edward Sern Yuen, Law Hai Yang, Yoon Chui Sheun, Tan Min-Han, Yap Yoon Sim, Ang Peter, Lee Ann Siew Gek

Abstract excerpt

It has been estimated that >1,000 genetic loci have yet to be identified for breast cancer risk. Here we report the first study utilizing targeted next-generation sequencing to identify single-nucleotide polymorphisms (SNP) associated with breast cancer risk. Targeted sequencing of 283 genes was performed in 240 women with early-onset breast cancer (≤40 years) or a family history of breast and/or ovarian cancer....

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Source

Identifiers

PMID: 28775167
DOI: 10.1158/0008-5472.CAN-17-0992

Genes

MAF
JAK2
NOTCH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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