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Article

A family-based, genome-wide association study of young-onset breast cancer: inherited variants and maternally mediated effects.

European journal of human genetics : EJHG - 1 Aug 2016

O'Brien Katie M, Shi Min, Sandler Dale P, Taylor Jack A, Zaykin Dmitri V, Keller Jean, Wise Alison S, Weinberg Clarice R

Abstract excerpt

Young-onset breast cancer shows certain phenotypic and etiologic differences from older-onset breast cancer and may be influenced by some distinct genetic variants. Few genetic studies of breast cancer have targeted young women and no studies have examined whether maternal variants influence disease in their adult daughters through prenatal effects. We conducted a family-based, genome-wide association study of...

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Identifiers

PMID: 26883092
DOI: 10.1038/ejhg.2016.11
PMCID: PMC4989201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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