Article

Performance comparison and in-silico harmonisation of commercial platforms for DNA methylome analysis by targeted bisulfite sequencing

2021-03-12

Abstract excerpt

DNA methylation is a key epigenetic modification in the regulation of cell fate and differentiation, and its analysis is gaining increasing importance in both basic and clinical research. Targeted Bisulfite Sequencing (TBS) has become the method of choice for the cost-effective, targeted analysis of the human methylome at base-pair resolution. Here we benchmarked five commercially available TBS platforms, includin...

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Literature Corpus work: ed457e00-aec5-5ae0-b4e5-7d35010589ad
DOI: 10.1101/2021.03.12.435105

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