Article
SMAP: a streamlined methylation analysis pipeline for bisulfite sequencing.
GigaScience - 1 Jan 2015
Gao Shengjie, Zou Dan, Mao Likai, Zhou Quan, Jia Wenlong, Huang Yi, Zhao Shancen, Chen Gang, Wu Song, Li Dongdong, Xia Fei, Chen Huafeng, Chen Maoshan, Ørntoft Torben F, Bolund Lars, Sørensen Karina D
Abstract excerpt
BACKGROUND: DNA methylation has important roles in the regulation of gene expression and cellular specification. Reduced representation bisulfite sequencing (RRBS) has prevailed in methylation studies due to its cost-effectiveness and single-base resolution. The rapid accumulation of RRBS data demands well designed analytical tools. FINDINGS: To streamline the data processing of DNA methylation from multiple RRBS...
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