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Performance comparison and in-silico harmonization of commercial platforms for DNA methylome analysis by targeted bisulfite sequencing

2021-09-15

Abstract excerpt

<title>Abstract</title> <p>DNA methylation is a key epigenetic modification in the regulation of cell fate and differentiation, and its analysis is gaining increasing importance in both basic and clinical research. Targeted Bisulfite Sequencing (TBS) has become the method of choice for the cost-effective, targeted analysis of the human methylome at base-pair resolution. Here we benchmarked five commercially avail...

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Literature Corpus work
7d38d3fa-4661-51c6-a60a-5e1e30d6ff39
DOI
10.21203/rs.3.rs-882163/v1
Open publication

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Performance comparison and in-silico harmonization of commercial platforms for DNA methylome analysis by targeted bisulfite sequencingDOI 10.21203/rs.3.rs-882163/v1
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