Article

ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data

2018-05-16

Abstract excerpt

Although human leukocyte antigen (HLA) genotyping based on amplicon, whole exome sequence (WES), and RNA sequence data has been achieved in recent years, accurate genotyping from whole genome sequence (WGS) data remains a challenge due to the low depth. Furthermore, there is no method to identify the sequences of unknown HLA types not registered in HLA databases. We developed a Bayesian model, called ALPHLARD, tha...

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Literature Corpus work: ecfa3d7b-fd7b-55d9-879c-7f15027db6dc
DOI: 10.1101/323766

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