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Article

The impact of next-generation sequencing technologies on HLA research.

Journal of human genetics - 1 Nov 2015

Hosomichi Kazuyoshi, Shiina Takashi, Tajima Atsushi, Inoue Ituro

Abstract excerpt

In the past decade, the development of next-generation sequencing (NGS) has paved the way for whole-genome analysis in individuals. Research on the human leukocyte antigen (HLA), an extensively studied molecule involved in immunity, has benefitted from NGS technologies. The HLA region, a 3.6-Mb segment of the human genome at 6p21, has been associated with more than 100 different diseases, primarily autoimmune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26311539
DOI: 10.1038/jhg.2015.102
PMCID: PMC4660052

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