Article

The Grapefruit Flavonoid Naringenin Inhibits Multiple Cardiac Ion Channels

2022-01-03

Abstract excerpt

Drinking fresh grapefruit juice is associated with a significant prolongation of the QT segment on the electrocardiogram (ECG) in healthy volunteers. Among the prominent flavonoids contained in citrus fruits, the flavanone naringenin is known to be a blocker of the human ether-a-go-go related gene (hERG) potassium channel. We hypothesized that naringenin could interfere with other major ion channels shaping the ca...

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Literature Corpus work: ec2f99b8-1d70-5fbe-ba83-63c224f5918a
DOI: 10.21203/rs.3.rs-1202805/v1

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