Article
In Silico Evaluation of the Potential Antiarrhythmic Effect of Epigallocatechin-3-Gallate on Cardiac Channelopathies.
Computational and mathematical methods in medicine - 1 Jan 2016
Boukhabza Maroua, El Hilaly Jaouad, Attiya Nourdine, El-Haidani Ahmed, Filali-Zegzouti Younes, Mazouzi Driss, Amarouch Mohamed-Yassine
Abstract excerpt
Ion channels are transmembrane proteins that allow the passage of ions according to the direction of their electrochemical gradients. Mutations in more than 30 genes encoding ion channels have been associated with an increasingly wide range of inherited cardiac arrhythmias. In this line, ion channels become one of the most important molecular targets for several classes of drugs, including antiarrhythmics....
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