Article
Peimine inhibits hERG potassium channels through the channel inactivation states.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 May 2017
Kan Liandi, Zhao Wei, Pan Lanying, Xu Jianwei, Chen Qingmao, Xu Kai, Xiao Liping, Chen Yuan
Abstract excerpt
BACKGROUND AND OBJECTIVE: Fritillaria is a Chinese traditional herb. It has a long history and many medicinal usages including antitussive, anti-inflammatory and pain relieving actions. It is also used as food. However, its cardiac safety has not been tested. Peimine is one of the main active compounds of Fritillaria. To be listed as an herb in the Chinese Pharmacopoeia, a special minimal percentage of Peimine in...
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