Article

Breaking point: the genesis and impact of structural variation in tumours

2018-11-19

Abstract excerpt

Somatic structural variants undoubtedly play important roles in driving tumourigenesis. This is evident despite the substantial technical challenges that remain in accurately detecting structural variants and their breakpoints in tumours and in spite of our incomplete understanding of the impact of structural variants on cellular function. Developments in these areas of research contribute to the ongoing discovery...

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Literature Corpus work: ebd2829c-28f9-56e5-ab83-b5b5845d8660
DOI: 10.12688/f1000research.16079.1

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