Article
Catalogue, cause, complexity and cure; the many uses of cancer genome sequence.
Current opinion in genetics & development - 1 Jun 2010
Wooster Richard, Bachman Kurtis E
Abstract excerpt
DNA sequence and bioinformatics technology have enabled the analysis of the cancer genome, revealing the vast genetic complexity of this disease. The patterns of somatic mutations are a rich archaeological record of the insults received by the genome that have added to our understanding of the mutagenic process. However, very few frequently mutated genes have been identified with the majority of somatic...
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