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Article

Somatic variation and cancer: therapies lost in the mix.

Human genetics - 1 Jul 2011

Biankin Andrew V, Hudson Thomas J

Abstract excerpt

Cancer arises as a consequence of mutations in genomes of cancer cells, which over time allow them to proliferate and spread to distant sites. Large-scale sequencing of cancer genomes is revealing an increasing number of potential driver mutations that may allow specific targeting of cancer genes, proteins, and pathways. Comprehensive views of cancer genomes are also revealing enormous heterogeneity of mutation...

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Identifiers

PMID: 21643984
DOI: 10.1007/s00439-011-1010-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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