Article

An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA export

2025-02-26

Abstract excerpt

In eukaryotes, a crucial step in gene expression is the export of the mRNA out of nucleus. The conserved mRNA exporter Mex67-Mtr2 (NXF1-NXT1 in human) is a key factor in this process. In S. cerevisiae , it is recruited to the mRNA by the four export adaptors Hpr1, Nab2, Yra1 and Npl3 that play important yet poorly defined roles in nuclear mRNA export. Here, we show that an excess of Mex67 in nuclear mRNPs impairs...

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Literature Corpus work: eba7abf8-582f-5e81-86f8-975be79ed624
DOI: 10.1101/2025.02.26.640412

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An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA exportDOI 10.1101/2025.02.26.640412Read

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