Article
Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.
Molecular and cellular biology - 1 Nov 1998
Santos-Rosa H, Moreno H, Simos G, Segref A, Fahrenkrog B, Panté N, Hurt E
Abstract excerpt
We have identified between Mex67p and Mtr2p a complex which is essential for mRNA export. This complex, either isolated from yeast or assembled in Escherichia coli, can bind in vitro to RNA through Mex67p. In vivo, Mex67p requires Mtr2p for association with the nuclear pores, which can be abolish...
Topics
- Escherichia coli
- Fungal Proteins
- Microscopy, Fluorescence
- Microscopy, Immunoelectron
- Mutation
- Nuclear Envelope
- Nuclear Pore Complex Proteins
- Nuclear Proteins
- Nucleocytoplasmic Transport Proteins
- Porins
- RNA, Messenger
- RNA-Binding Proteins
- Recombinant Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins