Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p.

Nature - 11 Oct 2001

Strässer K, Hurt E

Abstract excerpt

The yeast nuclear protein Yra1p is an essential export factor for mRNA. Yra1p interacts directly with the mRNA transport factor Mex67p/Mtr2p, which is associated with the nuclear pore. Here, we report a genetic interaction between YRA1 and SUB2, the gene for a DEAD box helicase involved in splici...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Biological Transport
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Genes, Lethal

Share to Nucleocytoplasmic Transport Proteins

Share to RNA-Binding Proteins

Share to RNA Splicing

Source

Identifiers

PMID: 11675790
DOI: 10.1038/35098113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11675790-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p.PMID 11675790Read ↗

Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p.Semantic proximity Read ↗

Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability.Semantic proximity Read ↗

The DECD box putative ATPase Sub2p is an early mRNA export factor.Semantic proximity Read ↗

Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export.Semantic proximity Read ↗

An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA exportSemantic proximity Read ↗

Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.Semantic proximity Read ↗

Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery.Semantic proximity Read ↗

A genetic screen in Saccharomyces cerevisiae identifies new genes that interact with mex67-5, a temperature-sensitive allele of the gene encoding the mRNA export receptor.Semantic proximity Read ↗

Expression of the essential mRNA export factor Yra1p is autoregulated by a splicing-dependent mechanism.Semantic proximity Read ↗

A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport.Semantic proximity Read ↗

Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.Semantic proximity Read ↗

Quality control of MATa1 splicing and exon skipping by nuclear RNA degradation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.