Article
A genetic screen in Saccharomyces cerevisiae identifies new genes that interact with mex67-5, a temperature-sensitive allele of the gene encoding the mRNA export receptor.
Molecular genetics and genomics : MGG - 1 Jan 2009
Estruch Francisco, Peiró-Chova Lorena, Gómez-Navarro Natalia, Durbán Jordi, Hodge Christine, Del Olmo Marcellí, Cole Charles N
Abstract excerpt
The Mex67p protein, together with Mtr2p, functions as the mRNA export receptor in Saccharomyces cerevisiae by interacting with both mRNA and nuclear pore complexes. To identify genes that interact functionally with MEX67, we used transposon insertion to search for mutations that suppressed the temperature-sensitive mex67-5 allele. Four suppressors are described here. The screen revealed that mutant Mex67-5p, but...
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