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Article

A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport.

Current biology : CB - 15 Jun 2000

Duncan K, Umen J G, Guthrie C

Abstract excerpt

BACKGROUND: In the nucleus, mRNAs are bound by hnRNP proteins. A subset of hnRNP proteins shuttle between the nucleus and cytoplasm and are believed to promote mRNA export by acting as adaptors between mRNA and the transport machinery. The existence of multiple shuttling hnRNP proteins raises the question of whether differentially regulated, hnRNP-specific mRNA export pathways exist. RESULTS: We have determined...

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Source

Identifiers

PMID: 10873801
DOI: 10.1016/s0960-9822(00)00527-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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