Article

Tissue-specific impacts of aging and genetics on gene expression patterns in humans

2021-11-19

Abstract excerpt

Age is the primary risk factor for many common human diseases including heart disease, Alzheimer’s dementias, cancers, and diabetes. Determining how and why tissues age differently is key to understanding the onset and progression of such pathologies. Here, we set out to quantify the relative contributions of genetics and aging to gene expression patterns from data collected across 27 tissues from 948 humans. We s...

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Literature Corpus work: eb789114-0f9c-5b55-b26b-c3ec54c67aab
DOI: 10.1101/2021.11.16.468753

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