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Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging

2023-05-26

Abstract excerpt

Complex diseases often exhibit sex-dimorphism in morbidity and prognosis, many of which are age-related. However, the underlying mechanisms of sex-dimorphic aging remain foggy, with limited studies across multiple tissues. We systematically analyzed ∼17,000 transcriptomes from 35 human tissues to quantitatively evaluate the individual and combined contributions of sex and age to transcriptomic variations. We disco...

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Literature Corpus work
5dbcd7f9-2c93-50e9-90ce-37a540009082
DOI
10.1101/2023.05.26.542373
Open publication

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Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human AgingDOI 10.1101/2023.05.26.542373
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