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Article

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases.

Scientific reports - 19 Oct 2015

Yang Jialiang, Huang Tao, Petralia Francesca, Long Quan, Zhang Bin, Argmann Carmen, Zhao Yong, Mobbs Charles V, Schadt Eric E, Zhu Jun, Tu Zhidong

Abstract excerpt

Aging is one of the most important biological processes and is a known risk factor for many age-related diseases in human. Studying age-related transcriptomic changes in tissues across the whole body can provide valuable information for a holistic understanding of this fundamental process. In this work, we catalogue age-related gene expression changes in nine tissues from nearly two hundred individuals collected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26477495
DOI: 10.1038/srep15145
PMCID: PMC4609956

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