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Global and tissue-specific transcriptomic dysregulation in human aging: Pathways and predictive biomarkers

28 Apr 2025

Abstract excerpt

Aging is a universal biological process that impacts all tissues, leading to functional decline and increased susceptibility to age-related diseases, particularly cardiometabolic disorders. While aging is characterized by hallmarks such as mitochondrial dysfunction, chronic inflammation, and dysregulated metabolism, the molecular mechanisms driving these processes remain incompletely understood, particularly in a...

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PMID: 40295347
DOI: 10.1007/s11357-025-01672-z

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