Article

Genetic dysregulation of gene expression and splicing during a ten-year period of human aging

2019-01-13

Abstract excerpt

<h4>Summary</h4> Molecular and cellular changes are intrinsic to aging and age-related diseases. Prior cross-sectional studies have investigated the combined effects of age and genetics on gene expression and alternative splicing; however, there has been no long-term, longitudinal characterization of these molecular changes, especially in older age. We performed RNA sequencing in whole-blood from the same individ...

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Literature Corpus work: 2da81b5a-2df6-539b-b965-d7d5863d65c9
DOI: 10.1101/519520

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