Back to search

Article

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

2016-07-14

Abstract excerpt

Gene expression changes with age have consequences for healthy aging and disease development. Here we investigate age-related changes in gene expression measured by RNA-seq in four tissues and the interplay between genotypes and age-related changes in expression. Using concurrently measured methylation array data from fat we also investigate the relationship between methylation, gene expression and age. We identif...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
52cc8cf1-1392-5871-9a6a-b54d023c4d49
DOI
10.1101/063883
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Age-dependent changes in mean and variance of gene expression across tissues in a twin cohortDOI 10.1101/063883
Select a neighboring publication to make it the new centre.