Article

Genome-wide Association Study Of Plasma Proteins Identifies Putatively Causal Genes, Proteins, And Pathways For Cardiovascular Disease

2017-05-12

Abstract excerpt

<h4>Summary</h4> Identifying genetic variants associated with circulating protein concentrations (pQTLs) and integrating them with variants from genome-wide association studies (GWAS) may illuminate the proteome’s causal role in disease and bridge a GWAS knowledge gap for hitherto unexplained SNP-disease associations. We conducted GWAS of 71 high-value proteins for cardiovascular disease in 6,861 Framingham Heart...

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Literature Corpus work: eb72828a-4ae2-5c25-8b6d-82a8cf0420bf
DOI: 10.1101/136523

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