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Identification of Circulating Proteins Associated With Blood Pressure.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2025

Xu Siqi, Wen Simin, Zong Xizeng, Wen Shifeng, Zhu Jianwei, Zheng Weipeng, Wang Zhiqiang, Cao Peihua, Liang Zhijiang, Ding Changhai, Zhang Yan, Ruan Guangfeng

Abstract excerpt

BACKGROUND: Circulating proteins in blood are involved in various physiological processes, but their contributions to blood pressure regulation remain partially understood. In traditional observational studies, identifying circulating proteins causally associated with blood pressure is challenging because of potentially unmeasured confounding and possible reverse causality. METHODS: Two-sample Mendelian...

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Biomarkers
Blood Pressure
Blood Proteins
Cross-Sectional Studies
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Quantitative Trait Loci

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PMID: 39624895
DOI: 10.1161/HYPERTENSIONAHA.124.24151

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