Article

A reproductive arrest program triggered by defects in Piwi and germ granules

2018-03-05

Abstract excerpt

In several species, Piwi/piRNA genome silencing defects lead to immediate sterility accompanied by heterochromatin dysfunction and transposon-induced genomic instability, which may cause Piwi mutant sterility. In C. elegans, Piwi pathway mutants transmit a heritable stress through germ cells that induces sterility after growth for several generations. We found that sterile Piwi pathway mutant germ cells displayed...

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Literature Corpus work: ea9ee2b8-a940-532b-9248-c974098e875f
DOI: 10.1101/276782

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