Article
PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans.
Cell - 4 Sept 1998
Kawasaki I, Shim Y H, Kirchner J, Kaminker J, Wood W B, Strome S
Abstract excerpt
Germ cells are distinct from somatic cells in their immortality, totipotency, and ability to undergo meiosis. Candidates for components that guide the unique germline program are the distinctive granules observed in germ cells of many species. We show that a component of germ granules is essentia...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cloning, Molecular
- Cytoplasmic Granules
- Epitopes
- Female
- Fertility
- Germ Cells
- Helminth Proteins
- Infertility
- Molecular Sequence Data
- Mutation
- RNA-Binding Proteins
- Sequence Alignment