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Article

PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans.

Cell - 4 Sept 1998

Kawasaki I, Shim Y H, Kirchner J, Kaminker J, Wood W B, Strome S

Abstract excerpt

Germ cells are distinct from somatic cells in their immortality, totipotency, and ability to undergo meiosis. Candidates for components that guide the unique germline program are the distinctive granules observed in germ cells of many species. We show that a component of germ granules is essential for fertility in C. elegans and that its primary function is in germline proliferation. This role has been revealed...

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PMID: 9741628
DOI: 10.1016/s0092-8674(00)81605-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans.PMID 9741628Read ↗

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Connecting the Dots: Linking Caenorhabditis elegans Small RNA Pathways and Germ Granules.Semantic proximity Read ↗

P Granule Assembly and Function in <i>Caenorhabditis elegans</i> Germ CellsSemantic proximity Read ↗

eIF4E assembly into <i>C. elegans</i> germ granules is essential for its repressive functionSemantic proximity Read ↗

Novel LOTUS-domain proteins are organizational hubs that recruit <i>C. elegans</i> Vasa to germ granulesSemantic proximity Read ↗

CSR-1 and P granules suppress sperm-specific transcription in the<i>C. elegans</i>germlineSemantic proximity Read ↗

ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans.Semantic proximity Read ↗

EGO-1, a Putative RNA-Directed RNA Polymerase, Promotes Germline Proliferation in Parallel With GLP-1/Notch Signaling and Regulates the Spatial Organization of Nuclear Pore Complexes and Germline P Granules in Caenorhabditis elegansSemantic proximity Read ↗

Systematic Identification of Germ Granule Proteins Reveals Specialized Roles in RNAi and Small RNA InheritanceSemantic proximity Read ↗

Systematic identification of germ granule proteins reveals specialized roles in RNAi and small RNA inheritance.Semantic proximity Read ↗

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